Immune Matters Episode 1, Blachy and Jessie, Wiskott Aldrich

In this episode of Immune Matters: a PIDTC Podcast, Dr. Jack McDonnell and Dr. Elie Haddad, along with guests Dr. Blachy Davila and Dr. Jessie Alexander, delve into Wiskott-Aldrich syndrome, a rare X-linked immunodeficiency affecting boys. They discuss the clinical manifestations, management strategies, and the importance of bone marrow transplantation as a definitive treatment. The conversation highlights a recent study analyzing transplant outcomes and conditioning regimens, emphasizing the need for timely intervention and collaboration in research to improve patient care.

The Primary Immune Deficiency Treatment Consortium (PIDTC) is a part of the Rare Diseases Clinical Research Network of the Office of Rare Diseases Research (ORDR), National Center for Advancing Translational Sciences (NCATS), National Institutes of Health (NIH).


This work was supported by the Division of Allergy, Immunology and Transplantation, National Institute of Allergy and Infectious Diseases (DAIT, NIAID) and the ORDR under cooperative agreements U54-AI082973 and U54-NS064808 and grants R13-AI094943 and 1R24AI184316-01.

The content and opinions expressed are solely the responsibility of the authors and do not represent the official policy or position of the NIAID, ORDR, NCATS, NIH, HRSA, or any other agency of the US Government.

Join Jack McDonnell, MD, a pediatric immunologist and assistant professor at Cleveland Clinic Lerner College of Medicine, and Elie Haddad, MD, PhD, a clinician-researcher in pediatric immunology, full professor at the University of Montreal, and head of the Immunology and Rheumatology department at CHU Sainte-Justine, as they explore the evolving world of immune deficiency and dysregulation.
Presented by the Primary Immune Deficiency Treatment Consortium (PIDTC), this podcast features conversations with leading experts, pioneering researchers, patients, and advocacy groups. Each episode uncovers cutting-edge research, clinical challenges, and personal stories—ensuring that the patient voice remains at the center of the discussion.
Whether you're a clinician, researcher, patient, or advocate, Immune Matters brings you the latest insights in diagnosis, treatment, and innovation in primary immune disorders.
Tune in to explore the science, the stories, and the future of immune health.
The Primary Immune Deficiency Treatment Consortium (PIDTC) is a part of the Rare Diseases Clinical Research Network of the Office of Rare Diseases Research (ORDR), National Center for Advancing Translational Sciences (NCATS), National Institutes of Health (NIH).
This work was supported by the Division of Allergy, Immunology and Transplantation, National Institute of Allergy and Infectious Diseases (DAIT, NIAID) and the ORDR under cooperative agreements U54-AI082973 and U54-NS064808 and grants R13-AI094943 and 1R24AI184316-01.
The content and opinions expressed are solely the responsibility of the authors and do not represent the official policy or position of the NIAID, ORDR, NCATS, NIH, HRSA, or any other agency of the US Government.

• No. of episodes: 2
• Latest episode: 2025-06-14
• Health & Fitness Medicine

Where can you listen?